From Enter the Gungeon Wiki
Nanomachines is a passive item.
- Grants two pieces of armor upon pickup.
- Grants a piece of armor every 4 times damage is taken.
Unused: College Ball - If the player has Ballot, it causes an unknown effect.
- The item name and function are references to the nanomachines which Senator Armstrong uses in the final battle of the game "Metal Gear Rising: Revengence" and his famous quote: "Nanomachines, son!"
- The unused "College Ball" synergy also references Armstrong; the Ballot references the fact that Armstrong runs for president, and the name of the synergy is another one of his quotes: "Played college ball, ya know."
- This item and function may also be a reference to Ratchet and Clank's Nanotech, which rebuilds the body whenever wounds are obtained in the series.
- The synergy "Pretty Good" is a reference to the popular quote from Metal Gear Solid, "You're pretty good".
- Its appearance may be a reference to the Nanites from Mystery Science Theater 3000.